PTK2 polyclonal antibody
产品名称： PTK2 polyclonal antibody
英文名称： PTK2 polyclonal antibody
产品编号： PAB1237
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against partial recombinant PTK2.
- Immunogen:
- Recombinant His fusion protein corresponding to amino acids 706-1052 of humanPTK2.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Purification:
- Affinity purification
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:5000)
Immunoprecipitation (2 ul)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Focal adhesion kinase: an essential kinase in the regulation of cardiovascular functions.
Vadali K, Cai X, Schaller MD.IUBMB Life. 2007 Nov;59(11):709-16.
- 2.
- RAFTK/Pyk2-mediated cellular signalling.
Avraham H, Park SY, Schinkmann K, Avraham S.Cell Signal. 2000 Mar;12(3):123-33.
- 3.
- Signaling through focal adhesion kinase.
Schlaepfer DD, Hauck CR, Sieg DJ.Prog Biophys Mol Biol. 1999;71(3-4):435-78.
- Entrez GeneID:
- 5747
- Gene Name:
- PTK2
- Gene Alias:
- FADK,FAK,FAK1,pp125FAK
- Gene Description:
- PTK2 protein tyrosine kinase 2
- Omim ID:
- 600758
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined. [provided by RefSeq
- Other Designations:
- focal adhesion kinase 1
- Interactome
