HRK polyclonal antibody
产品名称： HRK polyclonal antibody
英文名称： HRK polyclonal antibody
产品编号： PAB8770
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of HRK.
- Immunogen:
- A synthetic peptide corresponding to residues surrounding amino acids 50 of human HRK.
- Host:
- Rabbit
- Reactivity:
- Human
- Specificity:
- The antibody detects human Hrk fused with green fluorescent protein in In crude extracts of E. coli transfected with Hrk-GFP.
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Storage Buffer:
- In PBS, pH 7.2 (50% glycerol, 1% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C. For long term storage store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Western Blot
- Entrez GeneID:
- 8739
- Gene Name:
- HRK
- Gene Alias:
- DP5,HARAKIRI
- Gene Description:
- harakiri, BCL2 interacting protein (contains only BH3 domain)
- Omim ID:
- 603447
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 homology domain-3 (BH3) motif of BIK. HRK interacts with BCL2 and BCLXL via the BH3 domain, but not with the death-promoting BCL2-related proteins BAX, BAK, or BCLXS. HRK localizes to membranes of intracellular organelles in a pattern similar to that previously reported for BCL2 and BCLXL. [provided by RefSeq
- Other Designations:
- BCL2-interacting protein,activator of apoptosis Hrk,death protein 5,harakiri
- Related Disease